Colorectal Cancer Association of Canada Colorectal Cancer Research
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چکیده
Continuing Avastin beyond the time when advanced crc gets worse helps patients, according to new study reports. Patients who continued to receive avastin with a new chemotherapy regimen after their cancer first progressed lived almost 12 months longer than patients who got more chemo but stopped avastin. Both groups did better than those who had no further treatment at all. The BRITE (Bevacizumab Regimens: Investigation of treatment Effects and Safety) observed progress of 3 groups of patients when their cancer got worse after their first chemotherapy treatments. All patients had avastin as part of their first chemo, some continued it beyond that first cancer progressing. The 3 groups included: • No further treatment with either chemotherapy or avastin and overall survival was 12.6 months • Chemotherapy but no further avastin with overall survival being 19.9 months • Change in chemotherapy and continued avastin with an overall survival of 31.8 months
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